Athermal character of the solid state amorphization of lactose induced by ball-milling By J.F. Willart, V. Caron, Ronan Lefort, F. Dan de, D. Pr vost and
Informaci n del art culo Athermal character of the solid state amorphization of lactose induced by ball milling
Mar 04, 2015 Willart JF, Caron V, Lefort R, Dan de F, Pr vost D, Descamps M. Athermal character of the solid state amorphization of lactose induced by ball milling. Solid State Commun. 2004132106936. CAS Article Google Scholar 17. Van den Mooter G.
Athermal character of the solid state amorphization of lactose induced by ball milling
Sep 08, 2011 Willart JF, Caron V, Lefort R, Danede F, Prevost D, Descamps M. Athermal character of the solid state amorphization of lactose induced by ball milling. Solid State Comm. 20041326936. Article CAS Google Scholar 23. Lefort R, Caron V, Willart JF, Descamps M. Mutarotational kinetics and glass transition of lactose.
Feb 07, 2013 Willart JF, Caron V, Lefort R, Danede F, Prevost D, Descamps M. Athermal character of the solid state amorphization of lactose induced by ball milling. Solid State Commun. 2004132106936. Article CAS Google Scholar
solid state by mechanical milling. Moreover, compared to similar materials, the amorphization kinetics of lactulose is found to be very rapid and the amorphous state thus obtained appears to be very stable against recrystallization upon heating. These features make lactulose a model compound for this type of solid state transformation.
Milling Induced Solidstate Transformations. On the contrary milling can be used to induce voluntarily changes of state which makes it possible to produce new solid forms with interesting new capacities for example in pharmacy to obtain an amorphization which allows to improve dissolution properties of poorly soluble compounds Milling is then a green route of synthesis that avoids the use of a ...
Solid State NMR and DSC methods for quantifying the amorphous content in solid dosage forms an application to ball-milling of trehalose. International Journal of Pharmaceutics ,
presented since amorphous forms prepared by different means of amorphization from PHYSICS 123 at Indonesia University of Education
Solid State Amorphization of Pharmaceuticals - Molecular... reviews Solid State Amorphization of Pharmaceuticals J. F. Willart and M. Descamps Laboratoire de Dynamique et Structure des Mate riaux Mole culaires, UMR CNRS 8024, ERT 1066, UniVersite de Lille 1, Bat.
Jul 23, 2019 This information is used in a phase field model that includes defect nucleation and solid state amorphization. At each scale, the components of the model are validated by performing simulations of sucrose, lactose, acetaminophen, and gamma-indomethacin. ... Yasuda H and Mori H 1999 Deformation-induced amorphization in ball-milled silicon Philos ...
Aug 22, 2016 Each milling experiment was prepared by adding to the reactor a single milling ball also of stainless steel of 20 g, 3 g of powders mixed according to Bi 2 Te 3 stoichiometry, and sealed in Ar ...
A critical view on lactose-based drug formulation and device studies for dry powder inhalation Which are relevant and what interactions to expect ... 2004. Athermal character of the solid state amorphization of lactose induced by ball milling. ... Fine powder mixing an a vibratory ball mill.
Jun 14, 2018 Defect-induced solid state amorphization of molecular crystals. NASA Astrophysics Data System ADS Lei, Lei Carvajal, Teresa Koslowski, Marisol. 2012-04-01. We investigate the process of mechanically induced amorphization in small
Sep 15, 2011 Mutarotational Kinetics and Glass Transition of Lactose Ronan LEFORT1, Vincent CARON2, Jean-Franois WILLART2, Marc DESCAMPS2 1 GMCM - UMR CNRS 6626, 2LDSMM - UMR CNRS 8024 ERT 1018 Universit de R
character of the solid state amorphization of lactose induced by ball milling, 6 I. Colombo, G. Grassi, M. Grassi, Drug mechanochemical activation, J. Pharm. Sci. 98 Solid State
Solid state amorphization via grinding has extensively been studied for a long time. This research is concerned mainly with metallic systems and inorganic compounds 8 . However, in recent years a lot of effort has been taken by the Decamps group to put some insight into crystal-glass transformation induced by milling in organic materials ...
Feb 16, 2011 Solid-state amorphization of rebamipide and investigation on solubility and stability of the amorphous form. Drug Development and Industrial Pharmacy 2017 , 43 2 , 283-292.
May 01, 2007 Milling is a usual process used in the course of drug formulation, which however may change the physical nature of the end product. The diversity of the transformations of organic compounds upon milling has been widely demonstrated in the pharmaceutical literature. However, no effort has still been devoted to study the correlation between the nature of the transformation and the milling ...
Overview of milling techniques for improving the solubility of poorly water-soluble drugs. Javier Coxon. Download PDF. Download Full PDF Package. This paper. A short summary of this paper. 37 Full PDFs related to this paper. Read Paper.
1-s2.0-S0169409X1530020X-main - Free download as PDF File .pdf, Text File .txt or read online for free. Formulation development
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F. H. Allen, The Cambridge Structural Database a quarter of a million crystal structures and rising, Acta Crystallogr B Struct Sci. International Union of ...
Apr 01, 2018 Methods of amorphization and investigation of the amorphous state. PubMed. Einfal, Toma Planinek, Odon Hrovat, Klemen. 2013-09-01. The amorphous form of pharmaceutical mater
Druglactose co-micronization by jet milling to improve aerosolization properties of a powder for inhalation. Int. J. Pharm. 321 162-166 2006. 4. Bahl, D and R.H. Bogner. Amorphization of indomethacin by co-grinding with Neusilin US2 amorphization kinetics, physical stability and mechanism. Pharm. Res. 23 1-9 2006. 5.
Nov 30, 2020 Athermal character of the solid state amorphization of lactose induced by ball milling Solid State Commun. , 132 10 2004 , pp. 693 - 696 , 10.1016j.ssc.2004.09.007 Article Download PDF View Record in Scopus Google Scholar
Solid State NMR and DSC methods for quantifying the amorphous content in solid dosage forms an application to ball-milling of trehalose , International Journal of Pharmaceutics, 2004, 280, pp. 209. M. Descamps, J.F. Willart, E. Dudognon and V. Caron, Transformation of Pharmaceutical Compounds upon milling and comilling The role of Tg,
Feb 10, 2018 Willart JF, Descamps M 2008 Solid state amorphization of pharmaceuticals. Mol Pharm 56905920. ... Pr vost D, Descamps M 2004 Athermal character of the solid state amorphization of lactose induced by ball milling. Solid State Commun 13210693696.
Apr 03, 2012 We investigate the process of mechanically induced amorphization in small molecule organic crystals under extensive deformation. In this work, we develop a model that describes the amorphization of molecular crystals, in which the plastic response is calculated with a phase field dislocation dynamics theory in four materials acetaminophen, sucrose, -indomethacin, and aspirin.
Solid state reactions induced by high energy ball milling especially amorphization reactions in metallic systems have attracted a large amount of research work recently.1 5 This is because the high energy ball milling approach has been recognized as a complex process which can be applied to processing of advanced materials at low cost.
Apr 23, 2007 Milling crystalline compounds well below the glass transition temperature of the corresponding liquid induces a direct solid state vitrification cases of lactose, 18 trehalose, 17 and budesonide 19. This amorphization process is fundamentally different from the usual thermal quench of the melt as proved, for example, by the total absence of ...
Jun 25, 2011 Athermal character of the solid state amorphization of lactose induced by ball milling Willart, JF Caron, V Lefort, R Dand de, F Pr vost, D Decamps, M Transformation of pharmaceutical compounds upon milling and comilling the role of Tg
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Dec 01, 2004 The C p jump in the DSC run 2 reveals that this milled sample has also a clear glassy character. This indicates that, upon milling, lactose reaches a real glassy amorphous state and not a simple nanocrystalline state as it could be expected from